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NS3

Introduction

NS3

NS3 protein (P70) [INCLUDES: N-ter serine protease; C-ter NTPase and RNA helicase]

631 residues (AF009606 - isolate HCV-H77)

Structure

Full-length NS3
PDB:1cu1
[VIEW] 		HCV NS3 protein 1cu1 In blue, the NS3 protease domain with NS4A co-factor in red.
In yellow, the protease-helicase connecting domain.
In magenta, the helicase domain
NS3 protease
PDB:1jxp
[VIEW] 		HCV NS3 protease domain 1jxp In blue, the NS3 protease domain with NS4A co-factor in orange.
In purple, the zinc atom
NS3 helicase
PDB:1hei
[VIEW] 		HCV NS3 helicase domain 1hei In blue, the domain of the helicase.
In red, the domain of the helicase.
In green, the domain of the helicase.
In yellow, an oligonucleotides.

Alignment (complete sequences)